1 00:00:06,897 --> 00:00:09,218 Cigarettes aren’t good for us. 2 00:00:09,218 --> 00:00:13,864 That’s hardly news--we’ve known about the dangers of smoking for decades. 3 00:00:13,865 --> 00:00:16,859 But how exactly do cigarettes harm us? 4 00:00:16,859 --> 00:00:19,192 Let’s look at what happens as their ingredients 5 00:00:19,192 --> 00:00:20,850 make their way through our bodies, 6 00:00:20,850 --> 00:00:25,477 and how we benefit physically when we finally give up smoking. 7 00:00:25,478 --> 00:00:27,358 With each inhalation, 8 00:00:27,358 --> 00:00:31,158 smoke brings its more than 5,000 chemical substances 9 00:00:31,158 --> 00:00:33,765 into contact with the body’s tissues. 10 00:00:33,765 --> 00:00:37,443 From the start, tar, a black, resinous material, 11 00:00:37,444 --> 00:00:39,825 begins to coat the teeth and gums, 12 00:00:39,825 --> 00:00:43,708 damaging tooth enamel, and eventually causing decay. 13 00:00:43,707 --> 00:00:47,720 Over time, smoke also damages nerve-endings in the nose, 14 00:00:47,720 --> 00:00:50,006 causing loss of smell. 15 00:00:50,006 --> 00:00:51,814 Inside the airways and lungs, 16 00:00:51,814 --> 00:00:54,603 smoke increases the likelihood of infections, 17 00:00:54,603 --> 00:00:59,277 as well as chronic diseases like bronchitis and emphysema. 18 00:00:59,277 --> 00:01:01,707 It does this by damaging the cilia, 19 00:01:01,707 --> 00:01:07,067 tiny hairlike structures whose job it is to keep the airways clean. 20 00:01:07,066 --> 00:01:09,503 It then fills the alveoli, 21 00:01:09,504 --> 00:01:13,654 tiny air sacs that enable the exchange of oxygen and carbon dioxide 22 00:01:13,653 --> 00:01:15,257 between the lungs and blood. 23 00:01:15,257 --> 00:01:20,250 A toxic gas called carbon monoxide crosses that membrane into the blood, 24 00:01:20,251 --> 00:01:21,957 binding to hemoglobin 25 00:01:21,957 --> 00:01:23,560 and displacing the oxygen 26 00:01:23,561 --> 00:01:26,771 it would usually have transported around the body. 27 00:01:26,771 --> 00:01:30,379 That’s one of the reasons smoking can lead to oxygen deprivation 28 00:01:30,379 --> 00:01:32,953 and shortness of breath. 29 00:01:32,953 --> 00:01:35,120 Within about 10 seconds, 30 00:01:35,120 --> 00:01:38,896 the bloodstream carries a stimulant called nicotine to the brain, 31 00:01:38,897 --> 00:01:42,413 triggering the release of dopamine and other neurotransmitters 32 00:01:42,412 --> 00:01:43,688 including endorphins 33 00:01:43,688 --> 00:01:47,683 that create the pleasurable sensations which make smoking highly addictive. 34 00:01:47,683 --> 00:01:50,042 Nicotine and other chemicals from the cigarette 35 00:01:50,043 --> 00:01:53,006 simultaneously cause constriction of blood vessels 36 00:01:53,006 --> 00:01:55,942 and damage their delicate endothelial lining, 37 00:01:55,941 --> 00:01:57,674 restricting blood flow. 38 00:01:57,674 --> 00:02:00,956 These vascular effects lead to thickening of blood vessel walls 39 00:02:00,956 --> 00:02:03,470 and enhance blood platelet stickiness, 40 00:02:03,471 --> 00:02:06,055 increasing the likelihood that clots will form 41 00:02:06,055 --> 00:02:08,929 and trigger heart attacks and strokes. 42 00:02:08,929 --> 00:02:12,688 Many of the chemicals inside cigarettes can trigger dangerous mutations 43 00:02:12,688 --> 00:02:15,965 in the body’s DNA that make cancers form. 44 00:02:15,965 --> 00:02:18,955 Additionally, ingredients like arsenic and nickel 45 00:02:18,955 --> 00:02:21,524 may disrupt the process of DNA repair, 46 00:02:21,524 --> 00:02:25,443 thus compromising the body’s ability to fight many cancers. 47 00:02:25,443 --> 00:02:29,175 In fact, about one of every three cancer deaths in the United States 48 00:02:29,175 --> 00:02:31,218 is caused by smoking. 49 00:02:31,217 --> 00:02:33,570 And it’s not just lung cancer. 50 00:02:33,570 --> 00:02:36,937 Smoking can cause cancer in multiple tissues and organs, 51 00:02:36,937 --> 00:02:38,744 as well as damaged eyesight 52 00:02:38,745 --> 00:02:40,901 and weakened bones. 53 00:02:40,901 --> 00:02:43,110 It makes it harder for women to get pregnant. 54 00:02:43,110 --> 00:02:46,088 And in men, it can cause erectile dysfunction. 55 00:02:46,087 --> 00:02:47,784 But for those who quit smoking, 56 00:02:47,784 --> 00:02:49,763 there’s a huge positive upside 57 00:02:49,763 --> 00:02:53,328 with almost immediate and long-lasting physical benefits. 58 00:02:53,328 --> 00:02:57,009 Just 20 minutes after a smoker’s final cigarette, 59 00:02:57,009 --> 00:03:00,840 their heart rate and blood pressure begin to return to normal. 60 00:03:00,841 --> 00:03:04,259 After 12 hours, carbon monoxide levels stabilize, 61 00:03:04,258 --> 00:03:07,022 increasing the blood’s oxygen-carrying capacity. 62 00:03:07,022 --> 00:03:08,539 A day after ceasing, 63 00:03:08,539 --> 00:03:13,894 heart attack risk begins to decrease as blood pressure and heart rates normalize. 64 00:03:13,894 --> 00:03:15,170 After two days, 65 00:03:15,169 --> 00:03:20,093 the nerve endings responsible for smell and taste start to recover. 66 00:03:20,093 --> 00:03:23,519 Lungs become healthier after about one month, 67 00:03:23,520 --> 00:03:25,875 with less coughing and shortness of breath. 68 00:03:25,875 --> 00:03:28,998 The delicate hair-like cilia in the airways and lungs 69 00:03:28,998 --> 00:03:31,076 start recovering within weeks, 70 00:03:31,076 --> 00:03:35,340 and are restored after 9 months, improving resistance to infection. 71 00:03:35,340 --> 00:03:37,717 By the one-year anniversary of quitting, 72 00:03:37,717 --> 00:03:42,761 heart disease risk plummets to half as blood vessel function improves. 73 00:03:42,760 --> 00:03:44,025 Five years in, 74 00:03:44,025 --> 00:03:46,844 the chance of a clot forming dramatically declines, 75 00:03:46,844 --> 00:03:49,751 and the risk of stroke continues to reduce. 76 00:03:49,751 --> 00:03:53,352 After ten years, the chances of developing fatal lung cancer 77 00:03:53,352 --> 00:03:55,397 go down by 50%, 78 00:03:55,397 --> 00:04:00,168 probably because the body’s ability to repair DNA is once again restored. 79 00:04:00,169 --> 00:04:04,008 Fifteen years in, the likelihood of developing coronary heart disease 80 00:04:04,008 --> 00:04:07,522 is essentially the same as that of a non-smoker. 81 00:04:07,521 --> 00:04:10,817 There’s no point pretending this is all easy to achieve. 82 00:04:10,818 --> 00:04:13,640 Quitting can lead to anxiety and depression, 83 00:04:13,639 --> 00:04:15,581 resulting from nicotine withdrawal. 84 00:04:15,581 --> 00:04:19,291 But fortunately, such effects are usually temporary. 85 00:04:19,291 --> 00:04:23,979 And quitting is getting easier, thanks to a growing arsenal of tools. 86 00:04:23,980 --> 00:04:26,426 Nicotine replacement therapy through gum, 87 00:04:26,425 --> 00:04:27,654 skin patches, 88 00:04:27,654 --> 00:04:28,438 lozenges, 89 00:04:28,439 --> 00:04:29,352 and sprays 90 00:04:29,351 --> 00:04:32,344 may help wean smokers off cigarettes. 91 00:04:32,345 --> 00:04:35,458 They work by stimulating nicotine receptors in the brain 92 00:04:35,458 --> 00:04:37,850 and thus preventing withdrawal symptoms, 93 00:04:37,850 --> 00:04:40,758 without the addition of other harmful chemicals. 94 00:04:40,757 --> 00:04:42,469 Counselling and support groups, 95 00:04:42,470 --> 00:04:44,413 cognitive behavioral therapy, 96 00:04:44,413 --> 00:04:46,605 and moderate intensity exercise 97 00:04:46,605 --> 00:04:50,060 also help smokers stay cigarette-free. 98 00:04:50,060 --> 00:04:51,608 That’s good news, 99 00:04:51,608 --> 00:04:56,256 since quitting puts you and your body on the path back to health.