[00:13] For a really long time, [00:14] I had two mysteries that were hanging over me. [00:18] I didn't understand them [00:20] and, to be honest, I was quite afraid to look into them. [00:24] The first mystery was, I'm 40 years old, [00:27] and all throughout my lifetime, year after year, [00:30] serious depression and anxiety have risen, [00:34] in the United States, in Britain, [00:37] and across the Western world. [00:39] And I wanted to understand why. [00:43] Why is this happening to us? [00:45] Why is it that with each year that passes, [00:48] more and more of us are finding it harder to get through the day? [00:51] And I wanted to understand this because of a more personal mystery. [00:55] When I was a teenager, [00:56] I remember going to my doctor [00:58] and explaining that I had this feeling, like pain was leaking out of me. [01:03] I couldn't control it, [01:04] I didn't understand why it was happening, [01:06] I felt quite ashamed of it. [01:09] And my doctor told me a story [01:10] that I now realize was well-intentioned, [01:12] but quite oversimplified. [01:14] Not totally wrong. [01:15] My doctor said, "We know why people get like this. [01:18] Some people just naturally get a chemical imbalance in their heads -- [01:22] you're clearly one of them. [01:24] All we need to do is give you some drugs, [01:26] it will get your chemical balance back to normal." [01:28] So I started taking a drug called Paxil or Seroxat, [01:30] it's the same thing with different names in different countries. [01:33] And I felt much better, I got a real boost. [01:36] But not very long afterwards, [01:37] this feeling of pain started to come back. [01:39] So I was given higher and higher doses [01:41] until, for 13 years, I was taking the maximum possible dose [01:45] that you're legally allowed to take. [01:47] And for a lot of those 13 years, and pretty much all the time by the end, [01:50] I was still in a lot of pain. [01:52] And I started asking myself, "What's going on here? [01:55] Because you're doing everything [01:56] you're told to do by the story that's dominating the culture -- [02:00] why do you still feel like this?" [02:02] So to get to the bottom of these two mysteries, [02:05] for a book that I've written [02:06] I ended up going on a big journey all over the world, [02:09] I traveled over 40,000 miles. [02:10] I wanted to sit with the leading experts in the world [02:13] about what causes depression and anxiety [02:15] and crucially, what solves them, [02:17] and people who have come through depression and anxiety [02:19] and out the other side in all sorts of ways. [02:21] And I learned a huge amount [02:23] from the amazing people I got to know along the way. [02:26] But I think at the heart of what I learned is, [02:29] so far, we have scientific evidence [02:32] for nine different causes of depression and anxiety. [02:35] Two of them are indeed in our biology. [02:38] Your genes can make you more sensitive to these problems, [02:41] though they don't write your destiny. [02:43] And there are real brain changes that can happen when you become depressed [02:46] that can make it harder to get out. [02:48] But most of the factors that have been proven [02:50] to cause depression and anxiety [02:52] are not in our biology. [02:55] They are factors in the way we live. [02:58] And once you understand them, [02:59] it opens up a very different set of solutions [03:02] that should be offered to people [03:04] alongside the option of chemical antidepressants. [03:07] For example, [03:09] if you're lonely, you're more likely to become depressed. [03:12] If, when you go to work, you don't have any control over your job, [03:15] you've just got to do what you're told, [03:17] you're more likely to become depressed. [03:19] If you very rarely get out into the natural world, [03:22] you're more likely to become depressed. [03:23] And one thing unites a lot of the causes of depression and anxiety [03:27] that I learned about. [03:28] Not all of them, but a lot of them. [03:30] Everyone here knows [03:32] you've all got natural physical needs, right? [03:34] Obviously. [03:35] You need food, you need water, [03:38] you need shelter, you need clean air. [03:40] If I took those things away from you, [03:42] you'd all be in real trouble, real fast. [03:44] But at the same time, [03:46] every human being has natural psychological needs. [03:50] You need to feel you belong. [03:52] You need to feel your life has meaning and purpose. [03:55] You need to feel that people see you and value you. [03:57] You need to feel you've got a future that makes sense. [04:00] And this culture we built is good at lots of things. [04:03] And many things are better than in the past -- [04:05] I'm glad to be alive today. [04:07] But we've been getting less and less good [04:09] at meeting these deep, underlying psychological needs. [04:13] And it's not the only thing that's going on, [04:16] but I think it's the key reason why this crisis keeps rising and rising. [04:20] And I found this really hard to absorb. [04:24] I really wrestled with the idea [04:26] of shifting from thinking of my depression as just a problem in my brain, [04:31] to one with many causes, [04:32] including many in the way we're living. [04:34] And it only really began to fall into place for me [04:36] when one day, I went to interview a South African psychiatrist [04:40] named Dr. Derek Summerfield. [04:41] He's a great guy. [04:43] And Dr. Summerfield happened to be in Cambodia in 2001, [04:46] when they first introduced chemical antidepressants [04:50] for people in that country. [04:51] And the local doctors, the Cambodians, had never heard of these drugs, [04:55] so they were like, what are they? [04:56] And he explained. [04:58] And they said to him, [04:59] "We don't need them, we've already got antidepressants." [05:02] And he was like, "What do you mean?" [05:04] He thought they were going to talk about some kind of herbal remedy, [05:07] like St. John's Wort, ginkgo biloba, something like that. [05:11] Instead, they told him a story. [05:14] There was a farmer in their community who worked in the rice fields. [05:18] And one day, he stood on a land mine [05:20] left over from the war with the United States, [05:22] and he got his leg blown off. [05:23] So they him an artificial leg, [05:25] and after a while, he went back to work in the rice fields. [05:28] But apparently, it's super painful to work under water [05:30] when you've got an artificial limb, [05:32] and I'm guessing it was pretty traumatic [05:34] to go back and work in the field where he got blown up. [05:36] The guy started to cry all day, [05:39] he refused to get out of bed, [05:40] he developed all the symptoms of classic depression. [05:43] The Cambodian doctor said, [05:45] "This is when we gave him an antidepressant." [05:47] And Dr. Summerfield said, "What was it?" [05:50] They explained that they went and sat with him. [05:53] They listened to him. [05:56] They realized that his pain made sense -- [05:59] it was hard for him to see it in the throes of his depression, [06:01] but actually, it had perfectly understandable causes in his life. [06:05] One of the doctors, talking to the people in the community, figured, [06:09] "You know, if we bought this guy a cow, [06:11] he could become a dairy farmer, [06:13] he wouldn't be in this position that was screwing him up so much, [06:16] he wouldn't have to go and work in the rice fields." [06:18] So they bought him a cow. [06:20] Within a couple of weeks, his crying stopped, [06:22] within a month, his depression was gone. [06:24] They said to doctor Summerfield, [06:25] "So you see, doctor, that cow, that was an antidepressant, [06:28] that's what you mean, right?" [06:30] (Laughter) [06:31] (Applause) [06:34] If you'd been raised to think about depression the way I was, [06:37] and most of the people here were, [06:38] that sounds like a bad joke, right? [06:40] "I went to my doctor for an antidepressant, [06:42] she gave me a cow." [06:43] But what those Cambodian doctors knew intuitively, [06:46] based on this individual, unscientific anecdote, [06:49] is what the leading medical body in the world, [06:53] the World Health Organization, [06:55] has been trying to tell us for years, [06:57] based on the best scientific evidence. [07:00] If you're depressed, [07:02] if you're anxious, [07:04] you're not weak, you're not crazy, [07:08] you're not, in the main, a machine with broken parts. [07:12] You're a human being with unmet needs. [07:15] And it's just as important to think here about what those Cambodian doctors [07:19] and the World Health Organization are not saying. [07:21] They did not say to this farmer, [07:23] "Hey, buddy, you need to pull yourself together. [07:26] It's your job to figure out and fix this problem on your own." [07:29] On the contrary, what they said is, [07:31] "We're here as a group to pull together with you, [07:35] so together, we can figure out and fix this problem." [07:40] This is what every depressed person needs, [07:44] and it's what every depressed person deserves. [07:47] This is why one of the leading doctors at the United Nations, [07:50] in their official statement for World Health Day, [07:53] couple of years back in 2017, [07:54] said we need to talk less about chemical imbalances [07:57] and more about the imbalances in the way we live. [08:00] Drugs give real relief to some people -- [08:02] they gave relief to me for a while -- [08:05] but precisely because this problem goes deeper than their biology, [08:09] the solutions need to go much deeper, too. [08:12] But when I first learned that, [08:15] I remember thinking, [08:16] "OK, I could see all the scientific evidence, [08:19] I read a huge number of studies, [08:20] I interviewed a huge number of the experts who were explaining this," [08:23] but I kept thinking, "How can we possibly do that?" [08:26] The things that are making us depressed [08:28] are in most cases more complex than what was going on [08:30] with this Cambodian farmer. [08:32] Where do we even begin with that insight? [08:34] But then, in the long journey for my book, [08:38] all over the world, [08:39] I kept meeting people who were doing exactly that, [08:42] from Sydney, to San Francisco, [08:44] to São Paulo. [08:45] I kept meeting people who were understanding [08:48] the deeper causes of depression and anxiety [08:50] and, as groups, fixing them. [08:52] Obviously, I can't tell you about all the amazing people [08:55] I got to know and wrote about, [08:57] or all of the nine causes of depression and anxiety that I learned about, [09:00] because they won't let me give a 10-hour TED Talk -- [09:03] you can complain about that to them. [09:04] But I want to focus on two of the causes [09:06] and two of the solutions that emerge from them, if that's alright. [09:10] Here's the first. [09:12] We are the loneliest society in human history. [09:15] There was a recent study that asked Americans, [09:18] "Do you feel like you're no longer close to anyone?" [09:21] And 39 percent of people said that described them. [09:25] "No longer close to anyone." [09:26] In the international measurements of loneliness, [09:28] Britain and the rest of Europe are just behind the US, [09:31] in case anyone here is feeling smug. [09:33] (Laughter) [09:34] I spent a lot of time discussing this [09:36] with the leading expert in the world on loneliness, [09:38] an incredible man named professor John Cacioppo, [09:40] who was at Chicago, [09:42] and I thought a lot about one question his work poses to us. [09:44] Professor Cacioppo asked, [09:47] "Why do we exist? [09:48] Why are we here, why are we alive?" [09:50] One key reason [09:53] is that our ancestors on the savannas of Africa [09:56] were really good at one thing. [09:58] They weren't bigger than the animals they took down a lot of the time, [10:01] they weren't faster than the animals they took down a lot of the time, [10:04] but they were much better at banding together into groups [10:07] and cooperating. [10:09] This was our superpower as a species -- [10:11] we band together, [10:12] just like bees evolved to live in a hive, [10:15] humans evolved to live in a tribe. [10:17] And we are the first humans ever [10:22] to disband our tribes. [10:24] And it is making us feel awful. [10:27] But it doesn't have to be this way. [10:29] One of the heroes in my book, and in fact, in my life, [10:31] is a doctor named Sam Everington. [10:33] He's a general practitioner in a poor part of East London, [10:36] where I lived for many years. [10:38] And Sam was really uncomfortable, [10:40] because he had loads of patients [10:41] coming to him with terrible depression and anxiety. [10:44] And like me, he's not opposed to chemical antidepressants, [10:46] he thinks they give some relief to some people. [10:49] But he could see two things. [10:50] Firstly, his patients were depressed and anxious a lot of the time [10:54] for totally understandable reasons, like loneliness. [10:57] And secondly, although the drugs were giving some relief to some people, [11:01] for many people, they didn't solve the problem. [11:03] The underlying problem. [11:05] One day, Sam decided to pioneer a different approach. [11:08] A woman came to his center, his medical center, [11:11] called Lisa Cunningham. [11:12] I got to know Lisa later. [11:14] And Lisa had been shut away in her home with crippling depression and anxiety [11:18] for seven years. [11:20] And when she came to Sam's center, she was told, "Don't worry, [11:23] we'll carry on giving you these drugs, [11:25] but we're also going to prescribe something else. [11:28] We're going to prescribe for you to come here to this center twice a week [11:31] to meet with a group of other depressed and anxious people, [11:34] not to talk about how miserable you are, [11:37] but to figure out something meaningful you can all do together [11:41] so you won't be lonely and you won't feel like life is pointless." [11:44] The first time this group met, [11:47] Lisa literally started vomiting with anxiety, [11:49] it was so overwhelming for her. [11:51] But people rubbed her back, the group started talking, [11:53] they were like, "What could we do?" [11:55] These are inner-city, East London people like me, [11:58] they didn't know anything about gardening. [12:00] They were like, "Why don't we learn gardening?" [12:02] There was an area behind the doctors' offices [12:04] that was just scrubland. [12:05] "Why don't we make this into a garden?" [12:07] They started to take books out of the library, [12:09] started to watch YouTube clips. [12:11] They started to get their fingers in the soil. [12:13] They started to learn the rhythms of the seasons. [12:16] There's a lot of evidence [12:18] that exposure to the natural world [12:19] is a really powerful antidepressant. [12:21] But they started to do something even more important. [12:25] They started to form a tribe. [12:27] They started to form a group. [12:29] They started to care about each other. [12:31] If one of them didn't show up, [12:32] the others would go looking for them -- "Are you OK?" [12:35] Help them figure out what was troubling them that day. [12:38] The way Lisa put it to me, [12:39] "As the garden began to bloom, [12:42] we began to bloom." [12:44] This approach is called social prescribing, [12:46] it's spreading all over Europe. [12:48] And there's a small, but growing body of evidence [12:50] suggesting it can produce real and meaningful falls [12:53] in depression and anxiety. [12:55] And one day, I remember standing in the garden [12:59] that Lisa and her once-depressed friends had built -- [13:01] it's a really beautiful garden -- [13:03] and having this thought, [13:04] it's very much inspired by a guy called professor Hugh Mackay in Australia. [13:08] I was thinking, so often when people feel down in this culture, [13:12] what we say to them -- I'm sure everyone here said it, I have -- [13:15] we say, "You just need to be you, be yourself." [13:19] And I've realized, actually, what we should say to people is, [13:22] "Don't be you. [13:24] Don't be yourself. [13:26] Be us, be we. [13:28] Be part of a group." [13:30] (Applause) [13:33] The solution to these problems [13:36] does not lie in drawing more and more on your resources [13:39] as an isolated individual -- [13:41] that's partly what got us in this crisis. [13:43] It lies on reconnecting with something bigger than you. [13:45] And that really connects to one of the other causes [13:48] of depression and anxiety that I wanted to talk to you about. [13:51] So everyone knows [13:52] junk food has taken over our diets and made us physically sick. [13:56] I don't say that with any sense of superiority, [13:58] I literally came to give this talk from McDonald's. [14:01] I saw all of you eating that healthy TED breakfast, I was like no way. [14:04] But just like junk food has taken over our diets and made us physically sick, [14:10] a kind of junk values have taken over our minds [14:14] and made us mentally sick. [14:16] For thousands of years, philosophers have said, [14:19] if you think life is about money, and status and showing off, [14:23] you're going to feel like crap. [14:25] That's not an exact quote from Schopenhauer, [14:27] but that is the gist of what he said. [14:29] But weirdly, hardy anyone had scientifically investigated this, [14:32] until a truly extraordinary person I got to know, named professor Tim Kasser, [14:36] who's at Knox College in Illinois, [14:38] and he's been researching this for about 30 years now. [14:40] And his research suggests several really important things. [14:43] Firstly, the more you believe [14:47] you can buy and display your way out of sadness, [14:51] and into a good life, [14:53] the more likely you are to become depressed and anxious. [14:56] And secondly, [14:58] as a society, we have become much more driven by these beliefs. [15:02] All throughout my lifetime, [15:04] under the weight of advertising and Instagram and everything like them. [15:08] And as I thought about this, [15:10] I realized it's like we've all been fed since birth, a kind of KFC for the soul. [15:16] We've been trained to look for happiness in all the wrong places, [15:19] and just like junk food doesn't meet your nutritional needs [15:22] and actually makes you feel terrible, [15:25] junk values don't meet your psychological needs, [15:28] and they take you away from a good life. [15:30] But when I first spent time with professor Kasser [15:33] and I was learning all this, [15:35] I felt a really weird mixture of emotions. [15:37] Because on the one hand, I found this really challenging. [15:40] I could see how often in my own life, when I felt down, [15:43] I tried to remedy it with some kind of show-offy, grand external solution. [15:49] And I could see why that did not work well for me. [15:52] I also thought, isn't this kind of obvious? [15:55] Isn't this almost like banal, right? [15:57] If I said to everyone here, [15:58] none of you are going to lie on your deathbed [16:01] and think about all the shoes you bought and all the retweets you got, [16:04] you're going to think about moments [16:06] of love, meaning and connection in your life. [16:08] I think that seems almost like a cliché. [16:10] But I kept talking to professor Kasser and saying, [16:12] "Why am I feeling this strange doubleness?" [16:15] And he said, "At some level, we all know these things. [16:18] But in this culture, we don't live by them." [16:21] We know them so well they've become clichés, [16:23] but we don't live by them. [16:24] I kept asking why, why would we know something so profound, [16:27] but not live by it? [16:29] And after a while, professor Kasser said to me, [16:32] "Because we live in a machine [16:35] that is designed to get us to neglect what is important about life." [16:39] I had to really think about that. [16:40] "Because we live in a machine [16:42] that is designed to get us to neglect what is important about life." [16:46] And professor Kasser wanted to figure out if we can disrupt that machine. [16:50] He's done loads of research into this; [16:51] I'll tell you about one example, [16:53] and I really urge everyone here to try this with their friends and family. [16:57] With a guy called Nathan Dungan, he got a group of teenagers and adults [17:00] to come together for a series of sessions over a period of time, to meet up. [17:04] And part of the point of the group [17:06] was to get people to think about a moment in their life [17:09] they had actually found meaning and purpose. [17:12] For different people, it was different things. [17:14] For some people, it was playing music, writing, helping someone -- [17:18] I'm sure everyone here can picture something, right? [17:21] And part of the point of the group was to get people to ask, [17:24] "OK, how could you dedicate more of your life [17:26] to pursuing these moments of meaning and purpose, [17:29] and less to, I don't know, buying crap you don't need, [17:32] putting it on social media and trying to get people to go, [17:35] 'OMG, so jealous!'" [17:36] And what they found was, [17:38] just having these meetings, [17:39] it was like a kind of Alcoholics Anonymous for consumerism, right? [17:43] Getting people to have these meetings, articulate these values, [17:46] determine to act on them and check in with each other, [17:49] led to a marked shift in people's values. [17:52] It took them away from this hurricane of depression-generating messages [17:56] training us to seek happiness in the wrong places, [17:59] and towards more meaningful and nourishing values [18:02] that lift us out of depression. [18:05] But with all the solutions that I saw and have written about, [18:08] and many I can't talk about here, [18:11] I kept thinking, [18:12] you know: Why did it take me so long to see these insights? [18:16] Because when you explain them to people -- [18:18] some of them are more complicated, but not all -- [18:21] when you explain this to people, it's not like rocket science, right? [18:24] At some level, we already know these things. [18:26] Why do we find it so hard to understand? [18:29] I think there's many reasons. [18:31] But I think one reason is that we have to change our understanding [18:35] of what depression and anxiety actually are. [18:39] There are very real biological contributions [18:41] to depression and anxiety. [18:44] But if we allow the biology to become the whole picture, [18:47] as I did for so long, [18:49] as I would argue our culture has done pretty much most of my life, [18:53] what we're implicitly saying to people is, and this isn't anyone's intention, [18:57] but what we're implicitly saying to people is, [19:00] "Your pain doesn't mean anything. [19:02] It's just a malfunction. [19:03] It's like a glitch in a computer program, [19:06] it's just a wiring problem in your head." [19:10] But I was only able to start changing my life [19:13] when I realized your depression is not a malfunction. [19:18] It's a signal. [19:20] Your depression is a signal. [19:23] It's telling you something. [19:24] (Applause) [19:29] We feel this way for reasons, [19:31] and they can be hard to see in the throes of depression -- [19:34] I understand that really well from personal experience. [19:37] But with the right help, we can understand these problems [19:40] and we can fix these problems together. [19:43] But to do that, [19:44] the very first step [19:46] is we have to stop insulting these signals [19:48] by saying they're a sign of weakness, or madness or purely biological, [19:53] except for a tiny number of people. [19:55] We need to start listening to these signals, [19:58] because they're telling us something we really need to hear. [20:02] It's only when we truly listen to these signals, [20:07] and we honor these signals and respect these signals, [20:11] that we're going to begin to see [20:13] the liberating, nourishing, deeper solutions. [20:19] The cows that are waiting all around us. [20:23] Thank you. [20:24] (Applause)